While not explicit, the game contains suggestive themes and some partial nudity, particularly in certain adult-themed locations. There are also implied sexual situations and references.

This game features significant and often graphic violence, including shooting, stabbings, car accidents with visible injuries, and deaths. Some scenes depict blood and moderate gore, and the overall tone is very violent.

The game contains frequent and strong profanity, including the regular use of words like 'f*ck', 'sh*t', and 'c*nt' in various contexts, often during intense moments or conversations. Mild swear words like 'd*mn' and 'h*ll' are also present.

Alcohol and drug use are prevalent throughout the game, depicted as part of the characters' lifestyles and criminal activities. Smoking is also shown, and drug dealing and substance abuse are recurring themes.

While not a horror game, there are intense action sequences, moments of danger and suspense, and scenes that can be disturbing due to the themes of crime, violence, and corruption.

The narrative emphasizes loyalty to family and friends. Rebuilding one's life and seeking justice are underlying themes, though often pursued through illicit means.

Protagonist's journey involves navigating a corrupt environment. While driven by a desire for his family, his methods are criminal, offering limited positive behavioral examples.

Features a diverse cast representing various ethnicities and socio-economic backgrounds within the Los Santos setting. Characters display agency and play significant roles in the unfolding plot.

Offers a stylized portrayal of urban environments and social dynamics. Players may gain a basic understanding of cause and effect in decision-making within a simulated context.